Reagents
Test-specific reagents for specimen preparation and staining in the SDF-Index research method.
FRAGSIGN™ powered by SDF-Index™
Equip your laboratory for research DFI analysis.
Varen Health brings together test-specific reagents, laboratory training, SDF-Index software, and technical support so qualified teams can establish a consistent sperm DNA fragmentation research workflow.
For Research Use Only. Not for use in diagnostic procedures.
U.S. commercialization and support through Varen Health
Powered by SDF-Index™
Reagents · Training · Research analysis
Test-specific reagentsLaboratory trainingDFI/HDS research analysisTechnical support
Build laboratory capacity
Connect the bench workflow to the analysis.
FRAGSIGN brings the reagent and training workflow together with SDF-Index analytical software. Your team prepares research specimens, acquires data, and reviews the results within its own laboratory procedures.
- Establish a repeatable research workflow for your team.
- Connect specimen preparation, acquisition, and analytical review.
- Build staff capability through practical training.
- Access technical assistance as your research work develops.
Your research laboratoryStudy design, specimen handling, data acquisition, and research oversight
supported by
Varen HealthFRAGSIGN · Training · SDF-Index · Support
FRAGSIGN powered by SDF-Index
Four connected parts of a research workflow
Training
Instruction in preparation, flow-cytometry acquisition, quality review, software use, and research reporting.
Analysis
SDF-Index processing of laboratory-acquired FCS data for standardized DFI and HDS research outputs.
Support
Workflow planning, technical questions, and assistance for authorized laboratory teams.
From readiness to research
A practical path for your laboratory
Start with the team, instrumentation, and research purpose. Define the workflow before introducing it into routine research operations.
- 01
Assess
Discuss your research goals, laboratory personnel, and flow-cytometry capability.
- 02
Prepare
Plan the research workflow, test-specific reagents, and team training.
- 03
Establish
Evaluate the method under your laboratory’s research procedures and quality controls.
- 04
Acquire
Prepare research specimens and acquire flow-cytometry data in your laboratory.
- 05
Analyze
Review acquired data with SDF-Index for DFI/HDS analysis and research reporting.
Review Laboratory Readiness
Appropriate flow-cytometry capability and qualified laboratory personnel are required.
Technical evidence
Understand the findings and their limits.
Technical-stability testing followed 70 independently pipetted tests from 26 specimens. At 60 minutes after staining, the following results were observed relative to the 2.5-minute origin.
+1.04 ppDFI mean change
81.4%DFI results within ±5 pp
21.4%DFI category discordance
0.946DFI Lin concordance
DFI drift and category discordance increased at later timepoints. These are technical observations under the evaluated conditions; they do not establish diagnostic performance or patient outcomes.
Explore the workflow
Find the information your team needs.
Laboratory teams
Plan your research capability.
Review reagents, training, instrumentation, and team responsibilities.
Laboratory support Scientific reviewersExamine the technical evidence.
Explore the study design, complete timepoint results, and limitations.
Study findings General informationUnderstand DFI and HDS.
Learn what these research measurements describe and how to read their limits.
Research basicsFRAGSIGN powered by SDF-Index
Build your laboratory’s research capability.
Tell us about your team, instrumentation, and DFI research goals.