Reagents
Test-specific materials for the research wet-lab method.
FRAGSIGN™ powered by SDF-Index™
From research specimen to analytical output.
A connected workflow for sperm DNA fragmentation research: FRAGSIGN reagents and laboratory training, powered by SDF-Index analytical software. For Research Use Only. Not for use in diagnostic procedures.
Two brands. One connected workflow.
FRAGSIGN at the bench. SDF-Index in the analysis.
Varen supports the reagent and training workflow around SDF-Index. Your laboratory prepares research specimens and acquires flow-cytometry data; the software supports consistent analytical review and reporting.
- Test-specific reagents and laboratory workflow materials.
- Training for specimen preparation, acquisition, and quality review.
- Import of laboratory-acquired FCS data into SDF-Index.
- DFI/HDS outputs, analytical categories, and research reports.
- Technical support for authorized laboratory teams.
Powered by SDF-Index™
U.S. commercialization and support through Varen Health.
Analytical workflow
Four checkpoints for research data
Keep preparation, acquisition, quality review, and interpretation connected to the research protocol.
01
Import FCS
Bring laboratory-acquired flow-cytometry files into an organized analysis queue.
02
Review quality
Review acquisition timing, event rate, and analytical readiness.
03
Analyze
Calculate DFI and HDS using a consistent software workflow.
04
Report research results
Generate analytical output for review within the laboratory’s research procedures.
DFIresearch outputHDSresearch output
Illustrative concept. No specimen or patient data shown.
Research measurements
DFI and HDS, reported separately.
DFIDNA Fragmentation Index
The proportion of measured sperm events exhibiting increased susceptibility consistent with fragmented DNA under the method conditions.
HDSHigh DNA Stainability
The proportion of measured events exhibiting high DNA stainability, reported as a separate analytical parameter.
Research classifications organize analytical results. They are not a diagnosis, treatment recommendation, or prediction of an individual outcome.
Laboratory capacity
Support beyond the software
Team training
Preparation, acquisition, quality review, and software instruction.
Workflow planning
Support as the team evaluates and establishes its research procedures.
Technical assistance
Help with research workflow and authorized platform use.
Working together
A clear division of responsibilities
Varen Health provides
- FRAGSIGN test-specific reagents
- Laboratory and software training
- SDF-Index analytical access
- Research workflow support
Your laboratory provides
- Qualified personnel and instrumentation
- Research procedures and quality controls
- Specimen preparation and data acquisition
- Applicable oversight and requirements
Your research team reviews
- Study design and intended research use
- Acquisition and analysis quality
- Methods and their limitations
- Research reporting and conclusions
Already using SDF-Index?
Visit the product website for platform information and the laboratory sign-in route.
Explore FRAGSIGN for your research laboratory.
Start with your instrumentation, team, and analytical goals.